- Office Planning & Design, Brenham
- Office Supplies, Equipment & Office Furniture Stores, Brenham
- Oil & Gas Companies, Brenham
- Oil & Gas Exploration & Development, Brenham - Oil Field Exploration, Monitoring & Remediation
- Oil & Gas Field Machinery & Equipment Manufacturers, Brenham
- Oil & Gas Producers, Brenham - Companies
- Oil & Gas Well Drilling Services, Brenham
- Oil & Petroleum Products, Brenham - Merchant, Wholesalers, etc
- Oil Brokers, Brenham
- Oil Change & Lubrication, Brenham - Auto Oil & Quick Lube
- Oil Field Services Testing Measuring & Surveying, Brenham
- Oil Industry & Oil Field Equipment & Services, Brenham - Oil Companies
- Ophthalmologists, Brenham - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Brenham
- Opticians, Brenham
- Optometrists, Brenham - Eye Doctors, Physicians & Surgeons (Optometry)
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- Oral Surgeon, Brenham - Dentists - Oral & Maxillofacial Surgeons
- Ornamental Iron - Residential, Brenham - Wrought Iron Work Supplies, Parts, Gates, Railings, Stairs, Spirals, Fence, etc
- Ornamental Metal Work, Brenham - Steel, Iron, Bronze, etc
- Ornamental Nursery, Brenham
- Ornamental Nursery Products, Brenham
- Ornamental Nursery Services, Brenham
- Orthodontist, Brenham - Teeth Straightening, Invisalign & Dental Braces
- Other Building Materials & Supplies, Brenham
- Other Lodging, Brenham
- Outboard Motors, Brenham
- Outboard Motors Parts & Repair, Brenham
- Outdoor & Lawn & Garden Equipment Repair & Service, Brenham
- Outdoor Equipment & Accessories, Brenham
- Outpatient Services, Brenham - Outpatient Care
- Overhead Door, Brenham
- Oxygen & Respiratory Equipment & Supplies, Brenham - Oxygen Concentrator, Tank, Machine, etc
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