- Sand Gravel & Aggregate, Childress
- Satellite & Cable TV Equipment & Systems Repair & Service, Childress
- Satellite Dish Antennas & Equipment Dealers, Childress
- Satellite TV Service, Childress
- Seafood Restaurants, Childress
- Security & Surveillance System & Equipment, Childress
- Security Brokers & Dealers, Childress
- Security Services, Childress
- Senior Citizens Centers & Meals, Childress
- Septic Tank Installation & Repair, Childress - Septic Systems
- Septic Tank Pumping & Cleaning, Childress - Septic Systems
- Septic Tanks & Septic Systems Contractors, Childress - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Sewer & Drain Cleaning & Repair, Childress - Drain Cleaner & Installation Services
- Shoe Store - More, Childress
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- Shopping & Shopping Services, Childress
- Signs, Childress
- Snacks & Desserts, Childress
- Social Services & Welfare, Childress
- Specialty Stores, Childress
- Speech & Hearing Specialists, Childress
- Sports Medicine, Childress - Doctors, Physicians & Surgeons
- State Government, Childress
- Steak House Restaurants, Childress
- Steel & Metal Goods, Childress - Steel Distributors
- Stocks & Bond Brokers, Childress
- Surveyor Services, Childress - Surveying Service
- Swimming Pools Repair, Service, Supplies, Sale & Installation, Childress
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