- Obstetricians & Gynecologists, Floresville - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Occupational Health Care Professionals, Floresville
- Occupational Therapy, Floresville - Occupational Health Specialists
- Off Road Vehicles, Floresville
- Off Road Vehicles Parts & Accessories, Floresville
- Office Supplies, Equipment & Office Furniture Stores, Floresville
- Oil & Gas Companies, Floresville
- Oil & Gas Consultants, Floresville
- Oil & Petroleum Products, Floresville - Merchant, Wholesalers, etc
- Oil Change & Lubrication, Floresville - Auto Oil & Quick Lube
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- Oil Field Contractors, Floresville
- Oil Industry & Oil Field Equipment & Services, Floresville - Oil Companies
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Floresville
- Opticians, Floresville
- Optometrists, Floresville - Eye Doctors, Physicians & Surgeons (Optometry)
- Orthopedists, Floresville - Orthopedic Surgery Doctors, Physicians & Surgeons
- Other Building Materials & Supplies, Floresville
- Other Lodging, Floresville
- Outdoor & Lawn & Garden Equipment Repair & Service, Floresville
- Outdoor Equipment & Accessories, Floresville
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