- Obstetricians & Gynecologists, League City - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Office Buildings & Parks, League City
- Office Equipment & Supplies Manufacturers, League City
- Office Space on Rent, League City - Executive Suites, Meeting Rooms, Conference Rooms, Virtual Offices, etc
- Office Supplies, Equipment & Office Furniture Stores, League City
- Oil & Gas Producers, League City - Companies
- Oil & Petroleum Products, League City - Merchant, Wholesalers, etc
- Oil Change & Lubrication, League City - Auto Oil & Quick Lube
- Oil Industry & Oil Field Equipment & Services, League City - Oil Companies
- Oil Petroleum Wholesale, League City
- Oil Refinery, League City
- Ophthalmologists, League City - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Stores - Eyeglasses, Lenses & Sunglasses, League City
- Opticians, League City
- Optometrists, League City - Eye Doctors, Physicians & Surgeons (Optometry)
- Optometry Clinics, League City - Eye Clinics
- Oriental Restaurants, League City
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- Ornamental Iron - Residential, League City - Wrought Iron Work Supplies, Parts, Gates, Railings, Stairs, Spirals, Fence, etc
- Ornamental Metal Work, League City - Steel, Iron, Bronze, etc
- Ornamental Nursery, League City
- Ornamental Nursery Services, League City
- Orthodontist, League City - Teeth Straightening, Invisalign & Dental Braces
- Orthopedists, League City - Orthopedic Surgery Doctors, Physicians & Surgeons
- Other Attorneys & Lawyers, League City
- Other Attorneys & Lawyers, League City
- Other Building Materials & Supplies, League City
- Other Lawyers & Attorneys, League City
- Other Lodging, League City
- Outdoor & Lawn & Garden Equipment Repair & Service, League City
- Outdoor Equipment & Accessories, League City
- Outpatient Services, League City - Outpatient Care
- Overhead Door, League City
- Ownership Organizations, League City
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