- Machine Shop, Littlefield
- Machine Shop & Tool Repair Service, Littlefield
- Machinery, Supplies & Equipment - Business Supplies Related, Littlefield
- Mail Delivery Service, Littlefield
- Major Appliances, Littlefield - Household & Kitchen
- Management Consultants & Services, Littlefield
- Manicurists & Pedicurists, Littlefield
- Manufacturing, Littlefield
- Masonry Materials & Supplies, Littlefield
- Meat Market, Wholesale & Products, Littlefield
- Medical Supplies & Equipment, Littlefield
- Men's & Boys Clothing & Accessories Stores, Littlefield
- Mens & Boys Jeans & Western Wear Stores, Littlefield
- Mental Health Specialists, Littlefield - Psychologist, Psychiatrist, Psychotherapist, etc
- Merchandise Sales Events, Littlefield
- Merle Norman Cosmetics, Littlefield
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- Metal Buildings, Littlefield - Kits, Homes, Steel Buildings, etc
- Metal Repair Service & Blacksmith, Littlefield - Iron Works
- Methodist Church, Littlefield
- Mexican Restaurants, Littlefield
- Miscellaneous Agriculture, Littlefield
- Miscellaneous Government, Littlefield
- Miscellaneous Professional, Littlefield
- Mortgage Bankers & Correspondents, Littlefield
- Mortgage Companies, Littlefield
- Motor Vehicle, Littlefield
- Motor Vehicle Rental & Leasing, Littlefield
- Motorcycle Parts, Accessories & Dealers, Littlefield
- Moving Supplies & Equipment Rental, Littlefield
- Moving Truck Rental , Littlefield
- Muffler Shop & Exhaust Systems, Littlefield
- Museums, Littlefield
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