- Laboratories Dental, Roanoke
- Laboratories Medical, Roanoke
- Land Surveyor, Roanoke - Land Surveying Services
- Landscape Contractors & Designers, Roanoke
- Landscape Design & Installation, Roanoke
- Landscape Garden Services, Roanoke
- Landscaping, Roanoke
- Late Night Restaurants, Roanoke
- Latin American Restaurants, Roanoke
- Lawn & Garden Equipment & Supplies, Roanoke
- Lawn & Garden Services, Roanoke
- Lawn & Garden Sprinkler Systems, Roanoke
- Lawn Maintenance Services, Roanoke
- Lawyers & Attorneys, Roanoke
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- Legal & Tax Services, Roanoke
- Legal Professionals, Roanoke
- Libraries, Roanoke
- Licensed Counselors, Roanoke
- Life Insurance, Roanoke
- Liquor Stores, Roanoke
- Loans Personal, Roanoke
- Locks, Roanoke
- Locksmiths, Roanoke - Residence, Commercial, Safe & Auto Car Locksmith
- Locksmiths Equipment & Supplies, Roanoke
- Lodging, Roanoke
- Lodging Services, Roanoke
- Logistics Freight, Roanoke
- Long Haul Trucking Companies, Roanoke
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